Cannabinoid Resources


Endocannabinoid receptors in the brain

Cannabinoid science is one of the youngest fields in biology. The discovery of the endocannabinoid system (ECS) in the early 1990s, and the subsequent realization that it encompasses the largest regulatory system thus far discovered, is incredibly significant for future therapies. Up until that point, it was believed that the nervous system was the most extensive system in the human body. This system is responsible for, among other things, homeostasis in mammalian physiology; it pushes systems between red to green, if you will.

One way to conceptualize the Endocannabinoid System is: if the nervous system is the chemical highway system of the body (such as freeways and toll roads), then the ECS comprises the side streets, dirt roads, and tributary roads that lead into the larger highway system. The ECS talks to every cell in the body, feeding the larger central and peripheral nervous systems.


As it stands today it is thought to be the largest and most extensive receptor system in the body and it is the primary regulator of homeostasis in the body. Within humans, there’s is no disease process in the human body that in someway is related to this system. Even though ECS support through exogenous cannabinoid supplementation is typically recommended for more specific conditions, such as epilepsy, patients under observation often report additional benefits when taking cannabinoids.


Activates 5-HT1A Serotonin Receptor

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May help with anxiety, addiction, appetite, sleep, nausea, vomiting

Binds to TRPV1 Receptors

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May moderate pain, inflammation, body temperature

Blocks G Protein Receptor GPR55

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May decrease bone reabsorption and the spread of cancer cells

Activates Peroxisome Proliferator Activated Receptors (PPARs)

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Has been shown to produce anti-cancer effect and help with Alzheimer’s


Cannabidiol, commonly known as CBD, is one phytocannabinoid under investigation for its anxiolytic and anti-inflammatory effects, as well as its ability to reduce symptom severity with insomnia and chronic pain.


Lacking the widely known, and often controversial, psychoactive effects of ∆9-tetrahydrocannabinol (THC), research on cannabidiol has demonstrated symptom relief for a wide range of disorders.


This is due in no small part to its effects on activity in limbic and paralimbic areas of the brain and receptors throughout the body.

Formula30A 25mg capsules open bottle

Additional Industry Organizations

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CBD Education
Project CBD
Marijuana Policy Project logo
Legal Reform
Marijuana Policy Project
Veterans Cannabis Project logo
Veteran Access
Veterans Cannabis Project

Research & Studies

We started Formula30A after we noticed that the general cannabinoid market was rampant with misinformation, doubt, and products containing significantly less CBD than advertised (in some cases, none at all). Our core belief is that education on the endocannabinoid system is vital to achieving beneficial health outcomes with the clinical application of cannabinoids. Check out our research and the studies we are conducting:

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F30A Community

Central to everything we do is our motivation to increase access to healthy outcomes for those that most in need. To support this goal, we established the F30A Community with the purpose of lifting up and supporting various organizations in our industry that advocate for those who can benefit most from the research and application of cannabinoid-based remedies.

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